HER2 Positive and Triple Negative Breast Cancer: A Review
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Abstract
Background: Cancer is the most common cause of mortality and morbidity seen in all over the world. Breast cancer is the second most prevalent type of non-skin cancer and the fifth most common cause of cancer-related mortality worldwide, accounting for 10.4% of all cancer incidences among women. HER2 is a protein that plays a role in cell growth and differentiation accounts for 15-20% of HER2- Positive breast cancer. Lack of expression of Estrogen & Progesterone Receptor and the absence of human epidermal growth factor receptor 2 (HER2) and accounts for 15% of Triple negative breast cancer of all cases
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