HER2 Positive and Triple NegativeBreast Cancer: A Review

Abstract

Background: Cancer is the most common cause of
mortality and morbidity seen in all over the world.
Breast cancer is the second most prevalent type of
non-skin cancer and the fifth most common cause of
cancer-related mortality worldwide, accounting for
10.4% of all cancer incidences among women.
HER2 is a protein that plays a role in cell growth and
differentiation accounts for 15-20% of HER2-
Positive breast cancer. Lack of expression of
Estrogen & Progesterone Receptor and the absence
of human epidermal growth factor receptor 2
(HER2) and accounts for 15% of Triple negative
breast cancer of all cases