Colorectal Cancer Review

Abstract

Cancer had become a common disease worldwide and cancer related death is also increasing in various parts of the world in spite of increased screening and diagnostic facilities available with effective treatment modalities and modern technologies. The prevalence of different type of cancer varies with variation in the living environment, differences in the ethnicity, diet and life style. Early detection of cancer and availability of advanced health care system makes it possible to reduce cancer related mortalities. Life style modification, sedentary life style, processed food and fast-food consumption, lack of fibre rich food in the diet, stress causes alteration in the microenvironment of the cells leading to genetic changes and mutation. Mutation in the cellular level becomes the primary reason for
the development of cancer cells. Colorectal cancer prevalence, risk factors for the development of colorectal cancer, pathogenesis, diagnosis and various treatment modalities available are discussed in this article.