Systematic Review Onmicron needles Drug Delivery in the Management of Various Disorders
Main Article Content
Abstract
Microneedle transdermal distribution is a method of providing medicinal substances to specific organs or tissues that involves inserting very small needles into the stratum corneum, the skin's outermost layer. Many people feel that this procedure could
eventually replace the more common practice of administering medication to patients by injection. Microneedles (MNs) are a revolutionary form of drug administration that allows for the least invasive entry of medicinal substances into a variety of tissues, including skin. This review delves deeply into the use of microneedles in the diagnosis and treatment of a variety of medical conditions, including cancer, diabetes, obesity, neuropathic pain, neurological disorders, respiratory problems, wounds, acne, ophthalmic illnesses, and wound healing
References
S. Abdelghany, I. A. Tekko, L. Vora, E. Larrañeta, A. D. Permana, R. F. Donnelly.
Nanosuspension-Based Dissolving Microneedle Arrays for Intradermal Delivery of Curcumin.
Pharmaceutics. 2019;11(7):E308.
K. S. Ahmed, X. Shan, J. Mao, L. Qiu, J. Chen.
Dermaroller® microneedles-mediated transdermal delivery of doxorubicin and celecoxib co-loaded liposomes for enhancing anticancer effect.
Mater Sci Eng C. 2019;99:1448–1458.
B. Al-Qallaf, D. B. Das.
Optimizing microneedle arrays for transdermal drug delivery: extension to non-square distribution.
J Drug Target. 2009;17(2):108–122.
F. K. Aldawood, A. Andar, S. Desai.
A comprehensive review of microneedles: types, materials, processes, characterizations and applications.
Polymers. 2021;13(16):2815.
M. S. Arshad et al.
Fabrication and characterization of self-applicating heparin sodium microneedle patches.
J Drug Target. 2021;29(1):60–68.
M. Avcil, A. Çelik.
Microneedles in drug delivery: progress and challenges.
Micromachines. 2021;12(11):1321.
C. Bao et al.
Microneedle patch delivery of capsaicin-containing α-lactalbumin nanomicelles achieves potent anti-obesity effects.
Adv Funct Mater. 2021;31(20):2011130.
D. A. Bhagwat et al.
Capsaicin loaded solid SNEDDS for enhanced bioavailability and anticancer activity.
J Pharm Sci. 2021;110(1):280–291.
N. S. Rejinold et al.
Curcumin-loaded biocompatible thermoresponsive polymeric nanoparticles for cancer drug delivery.
J Colloid Interface Sci. 2011;360(1):39–51.
H. Xu, S. Li, Y. S. Liu.
Nanoparticles in diagnosis and treatment of vascular aging and related diseases.
Signal Transduct Target Ther. 2022;7(1).
N. B. Banarase, C. D. Kaur.
Whole whey stabilized oleanolic acid nanosuspension: formulation and evaluation.
J Drug Deliv Sci Technol. 2022;67:103001.
C. D. Nguyen et al.
Pharmacokinetic improvement using microneedle patch delivering bee venom in neurodegeneration model.
Drug Deliv. 2022;29(1):2855–2867.
P. Prabhakaran et al.
Development of glitazones for activation of PGC-1α signaling via PPAR-γ agonism for Parkinson’s disease.
ACS Omega. 2023;8(7):6825–6837.
Y. Chen et al.
Fabrication of tunable length polymeric microneedle patches for controlled transdermal drug delivery.
RSC Adv. 2020;10(26):15541–15546.
S. H. Bariya, M. C. Gohel, T. A. Mehta, O. P. Sharma.
Microneedles: an emerging transdermal drug delivery system.
J Pharm Pharmacol. 2012;64(1):11–29.
C. H. Chen, V. B. H. Shyu, C. T. Chen.
Dissolving microneedle patches for transdermal insulin delivery in diabetic mice.
Materials. 2018;11(9):1625.
B. Z. Chen, M. Ashfaq, X. P. Zhang, J. N. Zhang, X. D. Guo.
In vitro and in vivo assessment of polymer microneedles for controlled drug delivery.
J Drug Target. 2018;26(8):720–729.
K. Cheung, D. B. Das.
Microneedles for drug delivery: trends and progress.
Drug Deliv. 2016;23(7):2338–2354.
M. Dangol et al.
Anti-obesity effect of caffeine-loaded dissolving microneedle patch in obese mice.
J Control Release. 2017;265:41–47.
R. F. Donnelly, T. R. R. Singh, A. D. Woolfson.
Microneedle-based drug delivery systems: microfabrication, drug delivery, and safety.
Drug Deliv. 2010;17(4):187–207.
A. GhavamiNejad et al.
Transdermal delivery using microneedle patch for hypoglycemia prevention.
Drug Deliv Transl Res. 2022;12(4):792–804.
J. Halder, S. Gupta, R. Kumari, G. D. Gupta, V. K. Rai.
Microneedle array: applications, advances, and clinical relevance.
J Pharm Innov. 2021;16(3):558–565.
D. A. A. Hamzah.
Transdermal microneedle patch for enhancing topical anaesthesia before IV insertion in paediatric patients.
A. R. J. Hutton et al.
Transdermal delivery of vitamin K using dissolving microneedles.
Int J Pharm. 2018;541(1–2):56–63.
K. Ita.
Transdermal delivery of drugs with microneedles: potential and challenges.
Pharmaceutics. 2015;7(3):90–105.
B. A. Jana et al.
Fabrication of carboxymethylcellulose-gelatin dissolving microneedle patch for insulin delivery.
J Pharm Innov. 2022.
N. Ahmad et al.
Curcumin nanoemulsion preparation and its effects in wound healing.
RSC Adv. 2019;9(35):20192–20206.
A. Khosraviboroujeni, S. Z. Mirdamadian, M. Minaiyan, A. Taheri.
3D printed PLA microneedle arrays for prolonged transdermal drug delivery.
Drug Deliv Transl Res. 2022;12(5):1195–1208.
X. Jiang, H. Zhao, W. Li.
Microneedle-mediated transdermal delivery of drug-carrying nanoparticles.
Front Bioeng Biotechnol. 2022;10:840395.
H. Khan, P. Mehta, H. Msallam, D. Armitage, Z. Ahmad.
Smart microneedle coatings for controlled delivery and biomedical analysis.
J Drug Target. 2014;22(9):790–795.
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